The same year this report was published, a splash to the eye unassociated with injury resulted in the Cercopithecine herpesvirus 1 infection and subsequent death of a research assistant at a primate research center (2,3). In rare instances, a publisher has elected to have a “zero” moving wall, so their current issues are available in JSTOR shortly after publication. The virus naturally infects macaque monkeys, resulting in disease that is similar to herpes simplex virus infection in humans. Veterinarians providing clinical and/or program oversight and support must have experience, training, and expertise necessary to appropriately evaluate the health and well-being of the species used, in the context of the animal use being carried out by the institution. Concerning xenotransplantations, porcine gammaherpesviruses must be considered as a zoonotic threat. In rare instances, a publisher has elected to have a “zero” moving wall, so their current issues are available in JSTOR shortly after publication. The epidemiology of herpesvirus papio infection in baboons closely parallels that of EBV infection in humans.
Using Meta-BASIC (http://basic.bioinfo.pl) (10), a highly sensitive fold recognition method that applies a comparison of sequence profiles enriched by predicted secondary structure, we predict that the UL24 gene encodes a novel PD-(D/E)XK endonuclease belonging to a large superfamily of restriction endonuclease-like fold proteins. Seven days after the first case was identified, a second macaque presented with a vesicular rash and was euthanized. Overall, 39% of macaques were shedding MaHV1 DNA; rates of DNA detection did not differ between sample types. The macaque was euthanized in light of a grave prognosis. In the family Nimaviridae, we only selected Shrimp white spot syndrome virus (WSSV, NC_003225) in genus Whispovirus. Virus images courtesy of CDC Public Health Image Library, Wellcome Images, U.S. The platyrrhines are New World monkeys found exclusively in Mexico and Central and South America.
All species of macaques appear to serve as the natural hosts of B virus. In the 1980s, Florida’s Game and Fresh Water Fish Commission became alarmed at the size of this invasive species’ population, both as a public health and public safety concern. The specificities of the gB-, gC-, and gD-ELISAs and of the mgG-ELISA were 100 and 97.5%, respectively. Construction of genomic recombinants between HVP2nv and HVP2ap isolates mapped the mouse neurovirulence determinant to within three genes. We observed no differences in the viral TK amino acid sequence between B virus isolates from rhesus monkeys and those from human zoonoses. The HVP-2 genome is 85% homologous to its closest relative, SA8. At the former site the membrane overlying the bud showed an electron opaque thickening which imparted to the mature particle an asymmetrical appearance.
Ben is a nationally recognized research expert in several areas, including zoonotic disease epidemiology, occupational health and safety in animal research environments, applied biostatistics, and animal welfare compliance. Furthermore, development and maintenance of true BV specific pathogen-free macaque colonies has proven dif cult. The mission of CM is to disseminate high-quality, peer-reviewed information that expands biomedical knowledge and promotes human and animal health through the study of laboratory animal disease, animal models of disease, and basic biologic mechanisms related to disease in people and animals. Originally, three virus types EEHV1A, EEHV1B and EEHV2 were identified, all members of the Proboscivirus genus within the Betaherpesvirinae. The population attributable risk of B virus seropositivity due to breeding was 22.7%, similar to the proportion of monkeys with B virus DNA in neuronal tissues subserving the genital region. B virus is not naturally found in other monkey species or apes, although this may occur through exposure to infected macaques. 57 1994 A cross sectional survey for B virus antibody in a colony of group housed rhesus macaques.
Ovaries from monkeys (age, 0 to 27 y) were serially sectioned (5 μm), stained, and photographed. Diffuse multifocal maculopapulovesicular rashes were present on the body, including mucocutaneous junctions. CeHV-1 is also known as B-virus or monkey B virus and as Herpesvirus simiae. Transmission may be facilitated by proximity, degree of physical contact between animals and humans, and the ability to be inoculated into the new host. This virus is a member of the subfamily Alphaherpesvirinae and is the most hazardous herpesvirus to man. Apple cider vinegar helps decrease the severity of herpes outbreaks due to its disinfectant, astringent, and anti-inflammatory properties. O’Sullivan, M.G.
Performing virus isolation on samples suspected of containing Cercopithecine herpesvirus 1 (monkey B virus [BV]) is dangerous due to the extreme neuropathogenicity of this virus in humans, and minimally requires biosafety level 3 (BSL-3) facilities. Unlike the simplexviruses of other primate species, only the unique short region of the HVS1 genome is bounded by inverted repeats. Herpes simplex virus 1 (HSV-1) is a large dsDNA virus that encodes its own DNA replication machinery, including enzymes involved in nucleotide metabolism. Monkey B virus (Macacine herpesvirus 1; BV) is endemic in macaques.